Cholestasis is a condition caused by rapidly developing acute or long-term chronic interruption in the excretion of bile a digestive fluid that helps the body process fat. There are many causes of cholestasis. Bile duct tumors, Cysts,Narrowing of the bile duct,Stones in the common bile duct,Pancreatitis,Pancreatic tumor or pseudocyst,Pressure on the bile ducts due to a nearby mass or tumor,Primary sclerosing cholangitis.
Bilirubin is the water-soluble pigment excreted in the bile. It is a yellow to orange bile pigment produced by the breakdown of Heme and reduction of biliverdin, it normally circulates in plasma and is taken up by liver cells and conjugated to form bilirubin diglucuronide.
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Failure of the liver cells to excrete bile, or obstruction of the bile ducts, can cause an increased amount of bilirubin in the body fluids and lead to obstructive jaundice. PBC Primary biliary cirrhosis is a disease in which the bile ducts in the liver are slowly destroyed.
Bile a yellow colour fluid produced in the liver plays a role in digesting food and helps rid your body of worn-out red blood cells, cholesterol and toxins. Liver inflammation caused by a virus.
Some other viruses, such as the Epstein-Barr virus and cytomegalovirus , can also cause hepatitis, but the liver is not their primary target. The term viral hepatitis can describe either a clinical illness or the histologic findings associated with the disease. Acute infection with a hepatitis virus may result in conditions ranging from subclinical disease to self-limited symptomatic disease to fulminant hepatic failure.
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Adults with acute hepatitis A or B are usually symptomatic. Persons with acute hepatitis C may be either symptomatic or asymptomatic. It is the condition of Liver in which the inflammation lasts for a time period of atleast 6 months. This condition ranges from mild to causing relatively little damage, or may be serious, causing many hepatocytes to be destroyed. It may lead critical conditions like cirrhosis and liver failure. Alcoholic hepatitis results due to heavy intake of alcohol resulting in liver inflammation.
The amount of alcohol consumed determines the risk and severity of liver damage. Women are at high risk for Alcoholic hepatitis. Symptoms include yellowing of skin, loss of appetite , fatigue and dark urine. Non-alcoholic fatty liver disease is the most common liver disease. This disease can occur in liver to people who consume little or no alcohol. It is one of the causes of fatty liver; occurring when fat is deposited in the liver due to other causes than excessive alcohol use.
Alhaddad, Maha M. Elsabaawy, Mohammed S. All Published work is licensed under a Creative Commons Attribution 4.
Immune suppression in chronic hepatitis B infection associated liver disease: A review
About Journal of Hepatitis. Hepatitis B spreads by contact with an infected person's blood, semen, or other body fluid. An infected woman can give hepatitis B to her baby at birth. If you get HBV, you may feel as if you have the flu. You may also have jaundice, a yellowing of skin and eyes, dark-colored urine, and pale bowel movements.
Some people have no symptoms at all. A blood test can tell if you have it. HBV usually gets better on its own after a few months. If it does not get better, it is called chronic HBV, which lasts a lifetime.
Chronic HBV can lead to cirrhosis scarring of the liver , liver failure, or liver cancer. There is a vaccine for HBV. It requires three shots. All babies should get the vaccine, but older children and adults can get it too. If you travel to countries where Hepatitis B is common, you should get the vaccine. Resources Reference Desk Find an Expert.
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